Liquid-Filled Hard Gelatin & HPMC Capsule Technologies

Liquid-filled capsule technology can be used for liquid and semi-solid fills into two-piece gelatin or HPMC capsules. The technology is a useful solution for formulation and delivery of difficult APIs not suitable for conventional solid dosage forms. Liquid-filled capsules are an economical alternative to expensive soft-gel manufacturing techniques, allowing for rapid evaluation of drug candidates in early clinical studies.

Liquid-filled capsules are a suitable technology for:
  • Insoluble, poorly bioavailable compounds

  • Potent compounds

  • Low melting point molecules

  • Molecules susceptible to oxidation

Liquid-filled capsules are available in a range of sizes and PharmaForm can develop liquid-filled capsules in either banded or unbranded formats. PharmaForm supports manufacturing of liquid-filled capsules from proof of concept to scale up. Following early-phase drug development, liquid-filled capsules can be easily converted to soft-gel dosage forms for scale-up and commercialization.

Contact Us

If you would like more information about our liquid-filled capsules technology, contact Elizabeth Hickman at 512 834-0449 x246.

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